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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YWHAZ All Species: 54.55
Human Site: S63 Identified Species: 85.71
UniProt: P63104 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63104 NP_001129171.1 245 27745 S63 R S S W R V V S S I E Q K T E
Chimpanzee Pan troglodytes XP_528202 382 42115 S200 R S S W R V V S S I E Q K T E
Rhesus Macaque Macaca mulatta XP_001098275 578 62565 S396 R S S W R V V S S I E Q K T E
Dog Lupus familis XP_850323 289 32637 S107 R S S W R V V S S I E Q K T E
Cat Felis silvestris
Mouse Mus musculus Q9CQV8 246 28068 S65 R S S W R V I S S I E Q K T E
Rat Rattus norvegicus P63102 245 27753 S63 R S S W R V V S S I E Q K T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509087 339 37959 S63 R S S W R V V S S I E Q K T E
Chicken Gallus gallus Q5ZKC9 245 27757 S63 R S S W R V V S S I E Q K T E
Frog Xenopus laevis Q91896 245 27711 S63 R S S W R V V S S I E Q K T E
Zebra Danio Brachydanio rerio Q5PRD0 244 27628 S63 R S S W R V I S S I E Q K T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29310 248 28209 S66 R S S W R V I S S I E Q K T E
Honey Bee Apis mellifera XP_391841 247 28058 S65 R S S W R V I S S I E Q K T E
Nematode Worm Caenorhab. elegans Q20655 248 28049 S65 R S S W R V I S S I E Q K T E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q01525 259 29143 I69 S W R I I S S I E Q K E E S R
Baker's Yeast Sacchar. cerevisiae P34730 273 31043 E68 W R I V S S I E Q K E E S K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.1 42.3 84 N.A. 86.5 99.5 N.A. 71.9 99.1 89.3 86.9 N.A. 80.6 82.5 80.2 N.A.
Protein Similarity: 100 64.1 42.3 84 N.A. 93.5 99.5 N.A. 71.9 100 94.6 94.6 N.A. 89.1 91 89.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 100 100 100 93.3 N.A. 93.3 93.3 93.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 62.5 60.8 N.A.
Protein Similarity: N.A. N.A. N.A. 72.9 72.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 7 7 0 94 14 7 0 94 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 7 7 0 40 7 0 87 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 7 0 87 7 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 87 0 0 0 % Q
% Arg: 87 7 7 0 87 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 7 87 87 0 7 14 7 87 87 0 0 0 7 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 87 0 % T
% Val: 0 0 0 7 0 87 54 0 0 0 0 0 0 0 0 % V
% Trp: 7 7 0 87 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _